TY - T1 - The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation SN - / UR - http://hdl.handle.net/10138/250888 T3 - A1 - Hiippala, Kaisa; Jouhten, Hanne; Ronkainen, Aki; Hartikainen, Anna; Kainulainen, Veera; Jalanka, Jonna; Satokari, Reetta A2 - PB - Y1 - 2018 LA - eng AB - The intestinal microbiota, composed of pro- and anti-inflammatory microbes, has an essential role in maintaining gut homeostasis and functionality. An overly hygienic lifestyle, consumption of processed and fiber-poor foods, or antibiotics are major factors modulating the microbiota and possibly leading to longstanding dysbiosis. Dysbiotic microbiota is characterized to have altered composition, reduced diversity and stability, as well as increased levels of lipopolysaccharide-containing, proinf... VO - IS - SP - OP - KW - 3111 Biomedicine; 3141 Health care science; commensal bacteria; intestinal health; next generation probiotics; dysbiosis; intestinal permeability; butyrate producing bacteria; anti-inflammatory; BUTYRATE-PRODUCING BACTERIA; ESCHERICHIA-COLI NISSLE; FECAL MICROBIOTA TRANSPLANTATION; CROSS-FEEDING INTERACTIONS; FAECALIBACTERIUM-PRAUSNITZII; AKKERMANSIA-MUCINIPHILA; BOWEL-DISEASE; ULCERATIVE-COLITIS; HUMAN FECES; IN-VITRO N1 - PP - ER -