TY - T1 - The Role of the Glycocalyx in the Pathophysiology of Subarachnoid Hemorrhage-Induced Delayed Cerebral Ischemia SN - / UR - http://hdl.handle.net/10138/335956 T3 - A1 - Schenck, Hanna; Netti, Eliisa; Teernstra, Onno; De Ridder, Inger; Dings, Jim; Niemelae, Mika; Temel, Yasin; Hoogland, Govert; Haeren, Roel A2 - PB - Y1 - 2021 LA - eng AB - The glycocalyx is an important constituent of blood vessels located between the bloodstream and the endothelium. It plays a pivotal role in intercellular interactions in neuroinflammation, reduction of vascular oxidative stress, and provides a barrier regulating vascular permeability. In the brain, the glycocalyx is closely related to functions of the blood-brain barrier and neurovascular unit, both responsible for adequate neurovascular responses to potential threats to cerebral homeostasis. An... VO - IS - SP - OP - KW - subarachnoid hemorrhage; aneurysm; delayed cerebral ischemia; glycocalyx; pathophysiology; review; ENDOTHELIAL SURFACE GLYCOCALYX; NITRIC-OXIDE; NEUROLOGICAL DEFICITS; LEUKOCYTE ADHESION; SMOKING-CESSATION; MOUSE MODEL; VASOSPASM; BARRIER; BRAIN; MICROCIRCULATION; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -