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T1  - The Water Extract of Juniperus communis L. Induces Cell Death and Sensitizes Cancer Cells to Cytostatic Drugs through p53 and PI3K/Akt Pathways 
SN  -  /  
UR  - http://hdl.handle.net/10138/303498 
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A1  - Raasmaja, Atso; Stenius, Ulla; Ghalali, Aram 
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Y1  - 2019 
LA  - eng 
AB  - Juniper (Juniperus communis L.) is a northern coniferous plant generally used as a spice and for nutritional purposes in foods and drinks. It was previously reported that juniper extract (JE) affects p53 activity, cellular stress, and gene expression induced cell death in human neuroblastoma cells. Therefore, the effects of juniper on p53 and Akt signaling was examined further in A549 lung, 22RV1 and DU145 prostate, and HepG2 liver cancer cells using Western blot, confocal microscopy, and MTT an... 
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KW  - cell death; plant extract; Juniperus communis L; p53; Akt; A549 non-small lung cancer cells; LUNG-CANCER; SURVIVAL; SH-SY5Y; NUCLEAR; 1182 Biochemistry, cell and molecular biology; 317 Pharmacy 
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