TY  -  
T1  - The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor 
SN  -  /  
UR  - http://hdl.handle.net/10138/335440 
T3  -  
A1  - Eesmaa, Ave; Yu, Li-Ying; Göös, Helka; Nõges, Kristofer; Kovaleva, Vera; Hellman, Maarit; Zimmermann, Richard; Jung, Martin; Permi, Perttu; Varjosalo, Markku; Lindholm, Paivi; Saarma, Mart 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress-regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non-neuronal damage. Although initially characterized as a secreted neurotrophic factor for midbrain dopamine neurons, MANF has recently gained more interest for its intracellular role in regulating the ER homeostasis, including serving as a cofactor of... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - ENDOPLASMIC-RETICULUM STRESS; NEUROTROPHIC FACTOR MANF; ER-STRESS; COMPREHENSIVE RESOURCE; BIP; BINDING; ATF6; ATP; DISSOCIATION; IRE1-ALPHA; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -