TY  -  
T1  - The effect of maternal alcohol and drug abuse on first trimester screening analytes: a retrospective cohort study 
SN  -  /  
UR  - http://hdl.handle.net/10138/319676 
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A1  - Lehikoinen, Anni; Voutilainen, Raimo; Romppanen, Jarkko; Heinonen, Seppo 
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Y1  - 2020 
LA  - eng 
AB  - Background: The purpose of this study was to determine whether first trimester trisomy screening (FTS) parameters are affected by alcohol and drug use. Methods: A routine combined FTS including measurements of maternal serum levels of free beta-human chorionic gonadotropin subunit (free beta-hCG) and pregnancy-associated plasma protein A (PAPP-A) were measured at 9-11 weeks of gestation, and fetal nuchal translucency thickness (NTT) at 11-13 weeks of gestation. In total 544 women with singleton ... 
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KW  - 3123 Gynaecology and paediatrics; First trimester screening; PAPP-A; free β-hCG; NUCHAL TRANSLUCENCY; alcohol; SMOKING; Small for gestational age; First trimester screening; PAPP-A; free beta-hCG; nuchal translucency; alcohol; smoking; small for gestational age; HUMAN CHORIONIC-GONADOTROPIN; PLASMA-PROTEIN-A; BIOCHEMICAL MARKERS; NUCHAL TRANSLUCENCY; BETA; PREGNANCY; BIOMARKERS; EXPOSURE; ETHANOL 
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