TY  -  
T1  - The role of OATP transporters in the active uptake of drugs into hepatocytes 
SN  -  /  
UR  - URN:NBN:fi-fe201801151256; http://hdl.handle.net/10138/135716 
T3  -  
A1  - Kahma, Helinä 
A2  -  
PB  - Helsingfors universitet 
Y1  - 2014 
LA  - eng 
AB  - Active transport processes in the basolateral (sinusoidal) membrane of hepatocytes have an important role in the hepatic clearance and overall disposition for several types of drugs. Organic anion transporting polypeptides (OATPs) expressed in the sinusoidal membrane have been shown to mediate the sodium-independent hepatic uptake of broad range of drugs and they have been associated with clinically relevant drug-drug interactions (DDIs) and genetic polymorphisms. The literature review focuses o... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - OATP; hepatic uptake; fluvastatin; entacapone; Biofarmaci; Biopharmacy; Biofarmasia 
N1  -   
PP  -  
ER  -