TY - T1 - Toisen polven virusspesifisten lääkkeiden kustannusvaikuttavuus C-hepatiitin hoidossa verrattuna standardihoitoon : järjestelmällinen kirjallisuuskatsaus SN - / UR - URN:NBN:fi-fe201801151377; http://hdl.handle.net/10138/199532 T3 - A1 - Konttinen, Riikka A2 - PB - Helsingfors universitet Y1 - 2017 LA - fin AB - Hepatitis C virus disease is transmitted through blood. Chronic hepatitis C causes liver damages such as liver fibrosis, liver cirrhosis, and hepatocellular carcinoma. It is estimated that there are approximately 20 000 - 30 000 patients infected with hepatitis C virus in Finland. For many years pegylated interferon and ribavirin has been standard of care. However standard of care causes side effects and an adequate treatment response can't be achieved with it. There have been effective direct-a... VO - IS - SP - OP - KW - hepatitis C; second generation direct-acting antiviral; cost-effectiveness; systematic review; C-hepatiitti; toisen polven virusspesifinen lääke; kustannusvaikuttavuus; järjestelmällinen kirjallisuuskatsaus; Socialfarmaci; Social Pharmacy; Sosiaalifarmasia N1 - PP - ER -