TY - T1 - Tongue Cancer Patients Can be Distinguished from Healthy Controls by Specific N-Glycopeptides Found in Serum SN - / UR - http://hdl.handle.net/10138/325748 T3 - A1 - Saraswat, Mayank; Mäkitie, Antti; Tohmola, Tiialotta; Dickinson, Amy; Saraswat, Shruti; Joenväärä, Sakari; Renkonen, Suvi A2 - PB - Y1 - 2018 LA - eng AB - Purpose Experimental design There are no blood biomarkers to detect early-stage oral cavity squamous cell carcinoma (OSCC) prior to clinical signs. Most OSCC incidence is associated with significant morbidity and poor survival. The authors aimed to use mass-spectrometry (MS) technology to find specific N-glycopeptides potentially serving as serum biomarkers for preclinical OSCC screening. Serum samples from 14 patients treated for OSCC (stage I or stage IV) with 12 age- and sex-matched controls ... VO - IS - SP - OP - KW - HNSCC; IgG; N-glycoproteomics; OSCC; transferrin; SQUAMOUS-CELL CARCINOMA; NECK-CANCER; OVARIAN-CANCER; GLYCOPROTEIN; HEAD; GLYCOSYLATION; BIOMARKERS; EXPRESSION; CONTRIBUTE; PROTEINS; 3125 Otorhinolaryngology, ophthalmology; 3122 Cancers N1 - PP - ER -