TY - T1 - Tonic GABAergic inhibition as a new way to regulate mesolimbic dopamine system SN - / UR - URN:ISBN:978-952-10-9637-2; http://hdl.handle.net/10138/42224 T3 - A1 - Vashchinkina, Elena A2 - PB - Helsingin yliopisto Y1 - 2013 LA - en AB - Dopamine (DA) neurons of the ventral tegmental area (VTA) are critical for decision-making and motivation and have also been implicated in the development of addictive behaviors. The activity of these neurons and the subsequent changes in DA concentrations in the target regions of the VTA are strictly regulated by both excitatory and inhibitory inputs. Among those inhibitory inputs, GABAergic transmission is mediated by phasic and tonic currents generated through different GABAA receptor subtype... VO - IS - SP - OP - KW - pharmacology N1 - PP - ER -