TY  -  
T1  - Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Mesocricetus auratus) with formulations containing pentamidine 
SN  -  /  
UR  - http://hdl.handle.net/10138/208069 
T3  -  
A1  - Comandolli-Wyrepkowski, Claudia Dantas; Grafova, Iryna; Naiff, Maricleide de Farias; Avella, Maurizio; Gentile, Gennaro; Grafov, Andriy; Ramos Franco, Antonia Maria 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration. The aim of this work was to evaluate the topical formulations containing pentamidine isethionate (PI) in the experimental treatment of cutaneous leishmaniasis (CL). Golden hamsters (Mesocricetus auratus) were infected in the nose with Leishmania (Leishmania) amazo... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - topical formulations; experimental treatment; pentamidine isethionate; animal model; Leishmania; CLINICAL-TRIAL; DOUBLE-BLIND; NEW-WORLD; STATE; DRUG; 116 Chemical sciences; 317 Pharmacy; 1172 Environmental sciences 
N1  -   
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ER  -