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T1  - UCHL5 expression associates with improved survival in lymph-node-positive rectal cancer 
SN  -  /  
UR  - http://hdl.handle.net/10138/222497 
T3  -  
A1  - Arpalahti, Leena; Hagstrom, Jaana; Mustonen, Harri; Lundin, Mikael; Haglund, Caj; Holmberg, Carina I. 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Colorectal cancer is among the three most common cancer types for both genders, with a rising global incidence. To date, prognostic evaluation is difficult and largely dependent on early detection and successful surgery. UCHL5/Uch37 is an integral part of the protein homeostasis network as one of the three deubiquitinating enzymes associated with the 26S proteasome. Here, we have investigated in colorectal cancer the possible association of UCHL5 tumor expression and patient survival. UCHL5 tumo... 
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OP  -  
KW  - Colorectal cancer; deubiquitination; prognosis; proteasome; UCHL5; DEUBIQUITINATING ENZYME UCH37; SMALL-MOLECULE INHIBITOR; PROTEASOME ACTIVITY; ACTIVATION; RESISTANCE; STRATEGY; USP14; 3122 Cancers 
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PP  -  
ER  -