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T1  - Ultraviolet B radiation modifies circadian time in epidermal skin and in subcutaneous adipose tissue 
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UR  - http://hdl.handle.net/10138/307275 
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A1  - Nikkola, Veera; Miettinen, Maija E.; Karisola, Piia; Grönroos, Mari; Ylianttila, Lasse; Alenius, Harri; Snellman, Erna; Partonen, Timo 
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Y1  - 2019 
LA  - eng 
AB  - Background Recent findings suggest that circadian time regulates cellular functions in the skin and may affect protection against ultraviolet radiation (UVR). It is not known, however, whether UVR through skin directly affects the expression of circadian genes. We investigated the effect of ultraviolet B (UVB) exposure on cryptochrome circadian clock 1 (CRY1), cryptochrome circadian clock 2 (CRY2), and circadian associated repressor of transcription (CIART) genes. Methods Healthy volunteers (n =... 
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KW  - 3121 General medicine, internal medicine and other clinical medicine; CRY1; CRY2; CIART; mRNA; gene; circadian associated repressor of transcription (CIART); CRY1; CRY2; gene; mRNA; BLUE-LIGHT PHOTORECEPTORS; INDUCED DNA-DAMAGE; CLOCK GENES; UV-RADIATION; EXPRESSION; PIGMENTATION; ERYTHEMA; MELANOPSIN; RHYTHMS 
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