TY - T1 - Validation of serological and molecular methods for diagnosis of zika virus infections SN - / UR - http://hdl.handle.net/10138/287679 T3 - A1 - Jääskeläinen, Anne J.; Korhonen, Essi M.; Huhtamo, Eili; Lappalainen, Maija; Vapalahti, Olli; Kallio-Kokko, Hannimari A2 - PB - Y1 - 2019 LA - eng AB - The laboratory confirmation of Zika virus (ZIKV) infection, and the differential diagnosis from other flavivirus infections such as dengue virus (DENV), often requires the use of several diagnostic test types. Cross-reactions and secondary infections complicate the serological diagnosis and specific viral RNA detection assays are often needed for confirming the diagnosis. The aim of this study was to validate serological and molecular methods for diagnosing ZIKV infection. This included the eval... VO - IS - SP - OP - KW - Zika; IgM; RT-qPCR; Diagnosis; Dengue; TBEV; TIME RT-PCR; CLINICAL PRESENTATION; WHOLE-BLOOD; DENGUE; VIREMIA; SPECIFICITY; COINFECTION; RNA; IGM; 3111 Biomedicine; 1182 Biochemistry, cell and molecular biology; 1183 Plant biology, microbiology, virology N1 - PP - ER -