TY  -  
T1  - Vascular Macrophages as Therapeutic Targets to Treat Intracranial Aneurysms 
SN  -  /  
UR  - http://hdl.handle.net/10138/329401 
T3  -  
A1  - Muhammad, Sajjad; Chaudhry, Shafqat Rasul; Dobreva, Gergana; Lawton, Michael T.; Niemelä, Mika; Hänggi, Daniel 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Aneurysmal subarachnoid hemorrhage (aSAH) is a highly fatal and morbid type of hemorrhagic strokes. Intracranial aneurysms (ICAs) rupture cause subarachnoid hemorrhage. ICAs formation, growth and rupture involves cellular and molecular inflammation. Macrophages orchestrate inflammation in the wall of ICAs. Macrophages generally polarize either into classical inflammatory (M1) or alternatively-activated anti-inflammatory (M2)-phenotype. Macrophage infiltration and polarization toward M1-phenotype... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - intracranial aneurysms; monocytes; macrophages; inflammation; subarachnoid hemorrhage; stroke; macrophage polarization; 3121 General medicine, internal medicine and other clinical medicine; 3112 Neurosciences 
N1  -   
PP  -  
ER  -