TY  -  
T1  - Veri-aivoesteen farmakokineettinen malli permeaation ja efluksin merkityksen tutkimiseen 
SN  -  /  
UR  - URN:NBN:fi-fe201801151119; http://hdl.handle.net/10138/24630 
T3  -  
A1  - Juuti, Hanne 
A2  -  
PB  - Helsingfors universitet 
Y1  - 2010 
LA  - fin 
AB  - The blood-brain barrier protects brain from xenobiotics that are in blood. Different in vivo and in vitro methods have been developed for studying blood brain barrier and those can be found in the literature. There are only few computational models pharmacokinetics of compounds in the brain. In this study permeability factors, which were measured in vitro or in vivo, were collected from literature. Additionally two different pharmacokinetic computer models of blood-brain barrier were described. ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - blood brain barrier; microdialysis; efflux; in silico; pharmacokinetic model; veri-aivoeste; mikrodialyysi; efluksi; in silico; farmakokineettinen malli; in silico; Biofarmaci; Biopharmacy; Biofarmasia 
N1  -   
PP  -  
ER  -