TY - T1 - X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area SN - / UR - http://hdl.handle.net/10138/320789 T3 - A1 - Virta, Johannes; Hannula, Markus; Tamminen, Ilmari; Lindfors, Katri; Kaukinen, Katri; Popp, Alina; Taavela, Juha; Saavalainen, Päivi; Hiltunen, Pauliina; Hyttinen, Jari; Kurppa, Kalle A2 - PB - Y1 - 2020 LA - eng AB - The often poorly orientated small-bowel mucosal biopsies taken for the diagnostics of celiac disease and other intestinal disorders are prone to misinterpretation. Furthermore, conventional histopathology has suboptimal sensitivity for early histopathological changes observed in short-term challenge studies. X-ray microtomography (micro-CT) is a promising new method for accurate imaging of human-derived biological samples. Here, we report that micro-CT could be utilized to create virtual reconst... VO - IS - SP - OP - KW - MICRO-COMPUTED TOMOGRAPHY; SMALL-INTESTINAL MUCOSA; CELIAC-DISEASE; MILD ENTEROPATHY; VILLOUS ATROPHY; GLUTEN; DIAGNOSIS; TRANSGLUTAMINASE; GUIDELINES; ANTIBODIES; 3111 Biomedicine N1 - PP - ER -