Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES)

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http://urn.fi/URN:NBN:fi-fe201804208342
Title: Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES)
Author: Verkola, Marie
Contributor: University of Helsinki, Faculty of Veterinary Medicine, Department of Equine and Small Animal Medicine
Publisher: Helsingfors universitet
Date: 2014
URI: http://urn.fi/URN:NBN:fi-fe201804208342
http://hdl.handle.net/10138/135180
Thesis level:
Abstract: Research on lesions in the equine stomach has concentrated mainly on equine gastric ulcer syndrome (EGUS). Lesions in the glandular area of the antrum and the pylorus, however, have so far received much less attention. The aim of this study was to contribute to the understanding of the histopathology of glandular lesions. The first part of the thesis consists of a thorough review of the literature on this subject. The literature review discusses the relevant literature on aetiology, pathophysiology, diagnosis, treatment and prevention of equine glandular gastritiserosion syndrome (EGGES). The second part is an empirical study in which the normal histopathology of the glandular mucosa of the equine stomach is examined and described, and then comparisons are made with a horse that has pathological evidence of EGGES. In addition, the gross lesions and the histopathological findings are presented as photographs. The horses for this study were selected from horses euthanased at the Equine Hospital of the Helsinki University Veterinary Teaching Hospital and sent to the Pathology and Parasitology unit of the Faculty of Veterinary Medicine, University of Helsinki for necropsy. The material was collected from August 2013 – February 2014. Only adult horses were included in this study. Altogether five stomachs were sampled. Two stomachs showed gross lesions and three appeared normal. However, only one normal-looking and one with lesions were suitable to be analysed for study purposes. The glandular lesions in the stomach with EGGES were shown to be more severe than any described in the literature before. However, the influence of the original illness and treatment of the horse could not be assessed. The study showed that in addition to erosions, hyperaemia, glandular atrophy, dysplasia and hyperplasia described in the literature before, severe ulcers and vasculitis can also be seen in the glandular stomach of horses.
Subject: equine
gastric ulcer
histopathology
Discipline: Equine Internal Medicine
Hevosten sisätaudit
Hästar internmedicin


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