Adaptation of neuromagnetic N1 without shifts in dipolar orientation

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http://hdl.handle.net/10138/136178

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Campbell , T & Neuvonen , T 2007 , ' Adaptation of neuromagnetic N1 without shifts in dipolar orientation ' , NeuroReport , vol. 18 , no. 4 , pp. 377-380 .

Title: Adaptation of neuromagnetic N1 without shifts in dipolar orientation
Author: Campbell, Tom; Neuvonen, Tuomas
Contributor: University of Helsinki, Helsinki Collegium for Advanced Studies
University of Helsinki, Department of Physiology
Date: 2007
Language: eng
Number of pages: 4
Belongs to series: NeuroReport
ISSN: 0959-4965
URI: http://hdl.handle.net/10138/136178
Abstract: 306-channel magnetoencephalography, coregistered with high-resolution volumetric magnetic resonance imaging, was used with 10 healthy participants to test if repetition adapts subsequent processing of sounds in a sequence and whether this adaptation influenced the orientation of the dipolar sources in the auditory cortex. Auditory Nlm responses to 1 kHz pure tones were indexed by clusters of sensors situated bilaterally over the temporal lobes. Nlm was augmented in amplitude at an interstimulus interval of 16 s relative to 1 s.This neuromagnetic amplitude augment occurred in dipoles in the vicinity of the auditory cortex, without significant shifts in the dipolar orientation. Recent repetition thus adapts auditory cortical neurons, in a manner subject to recovery after a period of silence.
Subject: 311 Basic medicine
312 Clinical medicine
318 Medical biotechnology
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