Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

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http://hdl.handle.net/10138/162573

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Khurana , V , Elson-Schwab , I , Fulga , T A , Sharp , K A , Loewen , C A , Mulkearns , E , Tyynelä , J , Scherzer , C R & Feany , M B 2010 , ' Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo ' , PLoS Genetics , vol. 6 , no. 7 , e1001026 . https://doi.org/10.1371/journal.pgen.1001026

Title: Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
Author: Khurana, Vikram; Elson-Schwab, Ilan; Fulga, Tudor A.; Sharp, Katherine A.; Loewen, Carin A.; Mulkearns, Erin; Tyynelä, Jaana; Scherzer, Clemens R.; Feany, Mel B.
Contributor: University of Helsinki, Department of Biochemistry and Developmental Biology
Date: 2010
Language: eng
Number of pages: 11
Belongs to series: PLoS Genetics
ISSN: 1553-7390
URI: http://hdl.handle.net/10138/162573
Subject: NEURONAL CEROID-LIPOFUSCINOSES
CATHEPSIN-D DEFICIENCY
CELL-CYCLE REENTRY
ALZHEIMERS-DISEASE
TRANSGENIC MICE
NEUROFIBRILLARY TANGLES
NEURODEGENERATIVE DISEASES
PARKINSONS-DISEASE
CASPASE-CLEAVAGE
GENE-EXPRESSION
311 Basic medicine
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