Mutation of the Fiber Shaft Heparan Sulphate Binding Site of a 5/3 Chimeric Adenovirus Reduces Liver Tropism

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Koski , A , Karli , E , Kipar , A , Escutenaire , S , Kanerva , A-M & Hemminki , A 2013 , ' Mutation of the Fiber Shaft Heparan Sulphate Binding Site of a 5/3 Chimeric Adenovirus Reduces Liver Tropism ' , PLoS One , vol. 8 , no. 4 , pp. e60032 . https://doi.org/10.1371/journal.pone.0060032

Title: Mutation of the Fiber Shaft Heparan Sulphate Binding Site of a 5/3 Chimeric Adenovirus Reduces Liver Tropism
Author: Koski, Anniina; Karli, Eerika; Kipar, Anja; Escutenaire, Sophie; Kanerva, Anna-Maija; Hemminki, Akseli
Contributor: University of Helsinki, Translational Cancer Biology (TCB) Research Programme
University of Helsinki, Departments of Faculty of Veterinary Medicine
University of Helsinki, Haartman Institute
University of Helsinki, Haartman Institute
University of Helsinki, Haartman Institute
Date: 2013-04-09
Language: eng
Number of pages: 15
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/164448
Subject: TARGETED ONCOLYTIC ADENOVIRUS
MEDIATED GENE DELIVERY
OVARIAN-CANCER CELLS
PHASE-I TRIAL
COAGULATION-FACTORS
NONHUMAN-PRIMATES
ORTHOTOPIC MODELS
SEROTYPE-5 FIBER
PROSTATE-CANCER
KUPFFER CELLS
3111 Biomedicine
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