Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

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Johnson , M R , Behmoaras , J , Bottolo , L , Krishnan , M L , Pernhorst , K , Santoscoy , P L M , Rossetti , T , Speed , D , Srivastava , P K , Chadeau-Hyam , M , Hajji , N , Dabrowska , A , Rotival , M , Razzaghi , B , Kovac , S , Wanisch , K , Grillo , F W , Slaviero , A , Langley , S R , Shkura , K , Roncon , P , De , T , Mattheisen , M , Niehusmann , P , O'Brien , T J , Petrovski , S , von Lehe , M , Hoffmann , P , Eriksson , J , Coffey , A J , Cichon , S , Walker , M , Simonato , M , Danis , B , Mazzuferi , M , Foerch , P , Schoch , S , De Paola , V , Kaminski , R M , Cunliffe , V T , Becker , A J & Petretto , E 2015 , ' Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus ' Nature Communications , vol. 6 , 6031 . DOI: 10.1038/ncomms7031

Title: Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
Author: Johnson, Michael R.; Behmoaras, Jacques; Bottolo, Leonardo; Krishnan, Michelle L.; Pernhorst, Katharina; Santoscoy, Paola L. Meza; Rossetti, Tiziana; Speed, Doug; Srivastava, Prashant K.; Chadeau-Hyam, Marc; Hajji, Nabil; Dabrowska, Aleksandra; Rotival, Maxime; Razzaghi, Banafsheh; Kovac, Stjepana; Wanisch, Klaus; Grillo, Federico W.; Slaviero, Anna; Langley, Sarah R.; Shkura, Kirill; Roncon, Paolo; De, Tisham; Mattheisen, Manuel; Niehusmann, Pitt; O'Brien, Terence J.; Petrovski, Slave; von Lehe, Marec; Hoffmann, Per; Eriksson, Johan; Coffey, Alison J.; Cichon, Sven; Walker, Matthew; Simonato, Michele; Danis, Benedicte; Mazzuferi, Manuela; Foerch, Patrik; Schoch, Susanne; De Paola, Vincenzo; Kaminski, Rafal M.; Cunliffe, Vincent T.; Becker, Albert J.; Petretto, Enrico
Contributor: University of Helsinki, Department of General Practice and Primary Health Care
Date: 2015-01
Language: eng
Number of pages: 11
Belongs to series: Nature Communications
ISSN: 2041-1723
URI: http://hdl.handle.net/10138/165252
Subject: GENOME-WIDE ASSOCIATION
NMDA RECEPTOR-ACTIVITY
SEIZURE SUSCEPTIBILITY
UP-REGULATION
EXPRESSION
BRAIN
INFLAMMATION
EXCITABILITY
EPILEPSIES
DISEASE
3111 Biomedicine
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