Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland : a cross-sectional study

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http://hdl.handle.net/10138/168119

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Teramura-Gronblad , M , Raivio , M , Savikko , N , Muurinen , S , Soini , H , Suominen , M & Pitkala , K 2016 , ' Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland : a cross-sectional study ' , Scandinavian Journal of Primary Health Care , vol. 34 , no. 3 , pp. 250-257 . https://doi.org/10.1080/02813432.2016.1207142

Title: Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland : a cross-sectional study
Author: Teramura-Gronblad, Mariko; Raivio, Minna; Savikko, Niina; Muurinen, Seija; Soini, Helena; Suominen, Merja; Pitkala, Kaisu
Contributor: University of Helsinki, Department of General Practice and Primary Health Care
University of Helsinki, Clinicum
University of Helsinki, Clinicum
University of Helsinki, Clinicum
University of Helsinki, Clinicum
Date: 2016
Language: eng
Number of pages: 8
Belongs to series: Scandinavian Journal of Primary Health Care
ISSN: 0281-3432
URI: http://hdl.handle.net/10138/168119
Abstract: Objective: This study aims to assess potentially severe class D drug-drug interactions (DDDIs) in residents 65 years or older in assisted living facilities with the use of a Swedish and Finnish drug-drug interaction database (SFINX). Design: A cross-sectional study of residents in assisted living facilities in Helsinki, Finland. Setting: A total of 1327 residents were assessed in this study. Drugs were classified according to the Anatomical Therapeutic Chemical (ATC) classification system and DDDIs were coded according to the SFINX. Main outcome measures: Prevalence of DDDIs, associated factors and 3-year mortality among residents. Results: Of the participants (mean age was 82.7 years, 78.3% were females), 5.9% (N=78) are at risk for DDDIs, with a total of 86 interactions. Participants with DDDIs had been prescribed a higher number of drugs (10.8 (SD 3.8) vs. 7.9 (SD 3.7), p Conclusions: Of the residents in assisted living, 5.9% were exposed to DDDIs associated with the use of a higher number of drugs. Physicians should be trained to find safer alternatives to drugs associated with DDDIs.
Subject: Assisted living
drug-drug interactions
Finland
general practice
mortality
PRIMARY-HEALTH-CARE
ELDERLY-PATIENTS
AMBULATORY-CARE
DATABASE
OUTPATIENTS
PREVALENCE
RESIDENTS
KNOWLEDGE
EXPOSURE
ALERTS
3121 Internal medicine
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