Lymphangiogenesis and Lymphangiogenic Growth Factors

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http://hdl.handle.net/10138/223859

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Hartiala , P & Saarikko , A M 2016 , ' Lymphangiogenesis and Lymphangiogenic Growth Factors ' , Journal of Reconstructive Microsurgery , vol. 32 , no. 1 , pp. 10-15 . https://doi.org/10.1055/s-0035-1544179

Title: Lymphangiogenesis and Lymphangiogenic Growth Factors
Author: Hartiala, Pauliina; Saarikko, Anne M.
Other contributor: University of Helsinki, Plastiikkakirurgian yksikkö

Date: 2016-01
Language: eng
Number of pages: 6
Belongs to series: Journal of Reconstructive Microsurgery
ISSN: 0743-684X
DOI: https://doi.org/10.1055/s-0035-1544179
URI: http://hdl.handle.net/10138/223859
Abstract: Lymphedema is a progressive disease caused by damage to the lymphatic network. Recent development in the fields of preclinical growth factor research and lymphedema microsurgery promise new hope for lymphedema patients. In this article, we review the latest results on basic research and highlight the role of specific growth factors in normal lymphatic development and several disease states. Lymph node transfer, a new promising method in reconstructive lymphatic microsurgery, is also dependent on the lymphatic vascular regrowth and lymphangiogenic growth factors. We discuss the scientific basis of lymph node transfer and therapeutic potential of lymphangiogenic growth factors in the treatment of lymphedema.
Subject: lymphangiogenesis
lymph node transfer
VEGF-C
LYMPH-NODE TRANSFER
CANCER-RELATED LYMPHEDEMA
GENE-THERAPY
POSTMASTECTOMY LYMPHEDEMA
HEREDITARY LYMPHEDEMA
SECONDARY LYMPHEDEMA
FACTOR-C
TRANSPLANTATION
METASTASIS
3126 Surgery, anesthesiology, intensive care, radiology
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