Silventoinen , K , Jelenkovic , A , Sund , R , Honda , C , Aaltonen , S , Yokoyama , Y , Tarnoki , A D , Tarnoki , D L , Ning , F , Ji , F , Pang , Z , Ordonana , J R , Sanchez-Romera , J F , Colodro-Conde , L , Burt , S A , Klump , K L , Medland , S E , Montgomery , G W , Kandler , C , McAdams , T A , Eley , T C , Gregory , A M , Saudino , K J , Dubois , L , Boivin , M , Haworth , C M A , Plomin , R , Oncel , S Y , Aliev , F , Stazi , M A , Fagnani , C , D'Ippolito , C , Craig , J M , Saffery , R , Siribaddana , S H , Hotopf , M , Sumathipala , A , Spector , T , Mangino , M , Lachance , G , Gatz , M , Butler , D A , Bayasgalan , G , Narandalai , D , Freitas , D L , Maia , J A , Harden , K P , Tucker-Drob , E M , Christensen , K , Skytthe , A , Kyvik , K O , Hong , C , Chong , Y , Derom , C A , Vlietinck , R F , Loos , R J F , Cozen , W , Hwang , A E , Mack , T M , He , M , Ding , X , Chang , B , Silberg , J L , Eaves , L J , Maes , H H , Cutler , T L , Hopper , J L , Aujard , K , Magnusson , P K E , Pedersen , N L , Aslan , A K D , Song , Y-M , Yang , S , Lee , K , Baker , L A , Tuvblad , C , Bjerregaard-Andersen , M , Beck-Nielsen , H , Sodemann , M , Heikkila , K , Tan , Q , Zhang , D , Swan , G E , Krasnow , R , Jang , K L , Knafo-Noam , A , Mankuta , D , Abramson , L , Lichtenstein , P , Krueger , R F , Mcgue , M , Pahlen , S , Tynelius , P , Duncan , G E , Buchwald , D , Corley , R P , Huibregtse , B M , Nelson , T L , Whitfield , K E , Franz , C E , Kremen , W S , Lyons , M J , Ooki , S , Brandt , I , Nilsen , T S , Inui , F , Watanabe , M , Bartels , M , van Beijsterveldt , T C E M , Wardle , J , Llewellyn , C H , Fisher , A , Rebato , E , Martin , N G , Iwatani , Y , Hayakawa , K , Rasmussen , F , Sung , J , Harris , J R , Willemsen , G , Busjahn , A , Goldberg , J H , Boomsma , D I , Hur , Y-M , Sorensen , T I A & Kaprio , J 2015 , ' The CODATwins Project : The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits ' , Twin Research and Human Genetics , vol. 18 , no. 4 , pp. 348-360 . https://doi.org/10.1017/thg.2015.29
Title: | The CODATwins Project : The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits |
Author: | Silventoinen, Karri; Jelenkovic, Aline; Sund, Reijo; Honda, Chika; Aaltonen, Sari; Yokoyama, Yoshie; Tarnoki, Adam D.; Tarnoki, David L.; Ning, Feng; Ji, Fuling; Pang, Zengchang; Ordonana, Juan R.; Sanchez-Romera, Juan F.; Colodro-Conde, Lucia; Burt, S. Alexandra; Klump, Kelly L.; Medland, Sarah E.; Montgomery, Grant W.; Kandler, Christian; McAdams, Tom A.; Eley, Thalia C.; Gregory, Alice M.; Saudino, Kimberly J.; Dubois, Lise; Boivin, Michel; Haworth, Claire M. A.; Plomin, Robert; Oncel, Sevgi Y.; Aliev, Fazil; Stazi, Maria A.; Fagnani, Corrado; D'Ippolito, Cristina; Craig, Jeffrey M.; Saffery, Richard; Siribaddana, Sisira H.; Hotopf, Matthew; Sumathipala, Athula; Spector, Timothy; Mangino, Massimo; Lachance, Genevieve; Gatz, Margaret; Butler, David A.; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Freitas, Duarte L.; Maia, Jose Antonio; Harden, K. Paige; Tucker-Drob, Elliot M.; Christensen, Kaare; Skytthe, Axel; Kyvik, Kirsten O.; Hong, Changhee; Chong, Youngsook; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J. F.; Cozen, Wendy; Hwang, Amie E.; Mack, Thomas M.; He, Mingguang; Ding, Xiaohu; Chang, Billy; Silberg, Judy L.; Eaves, Lindon J.; Maes, Hermine H.; Cutler, Tessa L.; Hopper, John L.; Aujard, Kelly; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Aslan, Anna K. Dahl; Song, Yun-Mi; Yang, Sarah; Lee, Kayoung; Baker, Laura A.; Tuvblad, Catherine; Bjerregaard-Andersen, Morten; Beck-Nielsen, Henning; Sodemann, Morten; Heikkila, Kauko; Tan, Qihua; Zhang, Dongfeng; Swan, Gary E.; Krasnow, Ruth; Jang, Kerry L.; Knafo-Noam, Ariel; Mankuta, David; Abramson, Lior; Lichtenstein, Paul; Krueger, Robert F.; Mcgue, Matt; Pahlen, Shandell; Tynelius, Per; Duncan, Glen E.; Buchwald, Dedra; Corley, Robin P.; Huibregtse, Brooke M.; Nelson, Tracy L.; Whitfield, Keith E.; Franz, Carol E.; Kremen, William S.; Lyons, Michael J.; Ooki, Syuichi; Brandt, Ingunn; Nilsen, Thomas Sevenius; Inui, Fujio; Watanabe, Mikio; Bartels, Meike; van Beijsterveldt, Toos C. E. M.; Wardle, Jane; Llewellyn, Clare H.; Fisher, Abigail; Rebato, Esther; Martin, Nicholas G.; Iwatani, Yoshinori; Hayakawa, Kazuo; Rasmussen, Finn; Sung, Joohon; Harris, Jennifer R.; Willemsen, Gonneke; Busjahn, Andreas; Goldberg, Jack H.; Boomsma, Dorret I.; Hur, Yoon-Mi; Sorensen, Thorkild I. A.; Kaprio, Jaakko |
Contributor organization: | Department of Social Research (2010-2017) Sociology Centre for Social Data Science, CSDS Department of Public Health Clinicum Jaakko Kaprio / Principal Investigator Institute for Molecular Medicine Finland Center for Population, Health and Society Population Research Unit (PRU) Genetic Epidemiology |
Date: | 2015-08 |
Language: | eng |
Number of pages: | 13 |
Belongs to series: | Twin Research and Human Genetics |
ISSN: | 1832-4274 |
DOI: | https://doi.org/10.1017/thg.2015.29 |
URI: | http://hdl.handle.net/10138/234293 |
Abstract: | For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m(2)) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts. We identified 67 twin projects, including both monozygotic (MZ) and dizygotic (DZ) twins, using various sources. We asked for individual level data on height and weight including repeated measurements, birth related traits, background variables, education and smoking. By the end of 2014, 48 projects participated. Together, we have 893,458 height and weight measures (52% females) from 434,723 twin individuals, including 201,192 complete twin pairs (40% monozygotic, 40% same-sex dizygotic and 20% opposite-sex dizygotic) representing 22 countries. This project demonstrates that large-scale international twin studies are feasible and can promote the use of existing data for novel research purposes. |
Subject: |
twins
height BMI heritability international comparisons BODY-MASS INDEX GENOME-WIDE ASSOCIATION HUMAN OBESITY ADOLESCENT DEVELOPMENT SWEDISH TWIN HEALTHY TWIN ADULT HEIGHT REARED APART 8 COUNTRIES REGISTRY 3111 Biomedicine 3123 Gynaecology and paediatrics 3142 Public health care science, environmental and occupational health |
Peer reviewed: | Yes |
Usage restriction: | openAccess |
Self-archived version: | publishedVersion |
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