Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials

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Scala , G , Marwah , V , Kinaret , P , Sund , J , Fortino , V & Greco , D 2018 , ' Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials ' , Data in Brief , vol. 19 , pp. 1046-1057 . https://doi.org/10.1016/j.dib.2018.05.107

Title: Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
Author: Scala, Giovanni; Marwah, Veer; Kinaret, Pia; Sund, Jukka; Fortino, Vittorio; Greco, Dario
Contributor organization: Institute of Biotechnology
Date: 2018-08
Language: eng
Number of pages: 12
Belongs to series: Data in Brief
ISSN: 2352-3409
DOI: https://doi.org/10.1016/j.dib.2018.05.107
URI: http://hdl.handle.net/10138/236001
Abstract: We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure. (C) 2018 Published by Elsevier Inc.
Subject: 1182 Biochemistry, cell and molecular biology
MICROARRAY
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Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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