A population-based study of the effect of pregnancy history on risk of stillbirth

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Raisanen , S , Hogue , C J R , Laine , K , Kramer , M R , Gissler , M & Heinonen , S 2018 , ' A population-based study of the effect of pregnancy history on risk of stillbirth ' , International Journal of Gynecology & Obstetrics , vol. 140 , no. 1 , pp. 73-80 . https://doi.org/10.1002/ijgo.12342

Title: A population-based study of the effect of pregnancy history on risk of stillbirth
Author: Raisanen, Sari; Hogue, Carol J. R.; Laine, Katariina; Kramer, Michael R.; Gissler, Mika; Heinonen, Seppo
Other contributor: University of Helsinki, Clinicum



Date: 2018-01
Language: eng
Number of pages: 8
Belongs to series: International Journal of Gynecology & Obstetrics
ISSN: 0020-7292
DOI: https://doi.org/10.1002/ijgo.12342
URI: http://hdl.handle.net/10138/237222
Abstract: ObjectiveTo examine the effect of pregnancy history on the risk of stillbirth. MethodsIn a population-based cross-sectional study, data were reviewed from all women aged at least 20years with singleton pregnancies in Finland between 2000 and 2010. The primary outcomestillbirthwas defined as fetal death after 22 gestational weeks or death of a fetus weighing at least 500g. ResultsAmong 604047 singleton pregnancies, the prevalence of stillbirth was 3.17 per 1000 deliveries. Prevalence was lowest for multiparous women without previous pregnancy loss after adjusting for major pregnancy complications associated with stillbirth (placenta previa, placental abruption, and pre-eclampsia) and other confounders. Relative to these women, stillbirth prevalence was higher among multiparous women with previous spontaneous abortion and/or stillbirth (adjusted odds ratio [aOR] 1.20, 95% confidence interval [CI] 1.05-1.36), nulliparous women with no previous pregnancy loss (aOR 1.23, 95% CI 1.10-1.38), and nulliparous women with prior spontaneous abortion (aOR 1.43, 95% CI 1.18-1.74). ConclusionPrevious pregnancy loss was found to be an independent risk factor for stillbirth, irrespective of the number of prior deliveries. Spontaneous abortion assessed as a part of pregnancy history was found to be an independent risk factor for stillbirth.
Subject: 3123 Gynaecology and paediatrics
Birth
Childbirth
Population register
Pregnancy history
Pregnancy outcome
Register
Spontaneous abortion
Stillbirth
METAANALYSIS
RECURRENCE
DISORDERS
REGISTER
QUALITY
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