COSCA (Core Outcome Set for Cardiac Arrest) in Adults : An Advisory Statement From the International Liaison Committee on Resuscitation

Show full item record



Permalink

http://hdl.handle.net/10138/302274

Citation

COSCA collaborators , Haywood , K & Castren , M 2018 , ' COSCA (Core Outcome Set for Cardiac Arrest) in Adults : An Advisory Statement From the International Liaison Committee on Resuscitation ' , Circulation , vol. 137 , no. 22 , pp. E783-E801 . https://doi.org/10.1161/CIR.0000000000000562

Title: COSCA (Core Outcome Set for Cardiac Arrest) in Adults : An Advisory Statement From the International Liaison Committee on Resuscitation
Author: COSCA collaborators; Haywood, Kirstie; Castren, Maaret
Contributor: University of Helsinki, Department of Diagnostics and Therapeutics
Date: 2018-05-29
Language: eng
Number of pages: 19
Belongs to series: Circulation
ISSN: 0009-7322
URI: http://hdl.handle.net/10138/302274
Abstract: Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on Resuscitation, sought to develop a consensus core outcome set for cardiac arrest for effectiveness trials. Core outcome sets are primarily intended for large, randomized clinical effectiveness trials (sometimes referred to as pragmatic trials or phase III/IV trials) rather than for pilot or efficacy studies. A systematic review of the literature combined with qualitative interviews among cardiac arrest survivors was used to generate a list of potential outcome domains. This list was prioritized through a Delphi process, which involved clinicians, patients, and their relatives/partners. An international advisory panel narrowed these down to 3 core domains by debate that led to consensus. The writing group refined recommendations for when these outcomes should be measured and further characterized relevant measurement tools. Consensus emerged that a core outcome set for reporting on effectiveness studies of cardiac arrest (COSCA) in adults should include survival, neurological function, and health-related quality of life. This should be reported as survival status and modified Rankin scale score at hospital discharge, at 30 days, or both. Health-related quality of life should be measured with >= 1 tools from Health Utilities Index version 3, Short-Form 36-Item Health Survey, and EuroQol 5D-5L at 90 days and at periodic intervals up to 1 year after cardiac arrest, if resources allow.
Subject: AHA Scientific Statements
cardiac arrest
consensus
quality of life
treatment outcome
QUALITY-OF-LIFE
MODIFIED RANKIN SCALE
CEREBRAL PERFORMANCE CATEGORY
TARGET TEMPERATURE MANAGEMENT
AMERICAN-HEART-ASSOCIATION
HEALTH UTILITIES INDEX
RANDOMIZED CONTROLLED-TRIAL
IMPEDANCE THRESHOLD DEVICE
PATIENT-REPORTED OUTCOMES
ACUTE STROKE TRIALS
3121 General medicine, internal medicine and other clinical medicine
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
CIR.0000000000000562.pdf 299.2Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record