Geographic origin as a determinant of left ventricular mass and diastolic function - the Cardiovascular Risk in Young Finns Study

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http://hdl.handle.net/10138/304183

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Vähämurto , L , Juonala , M , Ruohonen , S , Hutri-Kähönen , N , Kähönen , M , Laitinen , T , Tossavainen , P , Jokinen , E , Viikari , J , Raitakari , O T & Pahkala , K 2018 , ' Geographic origin as a determinant of left ventricular mass and diastolic function - the Cardiovascular Risk in Young Finns Study ' , Scandinavian Journal of Public Health , vol. 46 , no. 6 , pp. 630-637 . https://doi.org/10.1177/1403494818764782

Title: Geographic origin as a determinant of left ventricular mass and diastolic function - the Cardiovascular Risk in Young Finns Study
Author: Vähämurto, L.; Juonala, M.; Ruohonen, S.; Hutri-Kähönen, N.; Kähönen, M.; Laitinen, T.; Tossavainen, P.; Jokinen, E.; Viikari, J.; Raitakari, O. T.; Pahkala, K.
Contributor: University of Helsinki, Lastentautien yksikkö
Date: 2018-08
Language: eng
Number of pages: 8
Belongs to series: Scandinavian Journal of Public Health
ISSN: 1403-4948
URI: http://hdl.handle.net/10138/304183
Abstract: Aims: Eastern Finns have higher risk of coronary heart disease (CHD) and carotid intima-media thickness than western Finns although current differences in CHD risk factors are minimal. Left ventricular (LV) mass and diastolic function predict future cardiovascular events but their east-west differences are unknown. We examined the association of eastern/western baseline origin with LV mass and diastolic function. Methods : The study population included 2045 subjects of the Cardiovascular Risk in Young Finns Study with data from the baseline survey (1980) and the latest follow-up (2011) when echocardiography was performed at the age of 34-49 years. Results: Subjects with eastern baseline origin had in 2011 higher LV mass (139 +/- 1.0 vs. 135 +/- 1.0 g, p=0.006) and E/e-ratio indicating weaker LV diastolic function (4.86 +/- 0.03 vs. 4.74 +/- 0.03, p=0.02) than western subjects. Results were independent of age, sex, area of examination and CHD risk factors such as blood pressure and BMI (LV mass indexed with height: p
Subject: Atherosclerosis
Risk Factors
Echocardiography
Population
PRESERVED EJECTION FRACTION
INTIMA-MEDIA THICKNESS
HEART-FAILURE
ESSENTIAL-HYPERTENSION
MAGNETIC-RESONANCE
ECHOCARDIOGRAPHY
POPULATION
FINLAND
EVENTS
TRENDS
3142 Public health care science, environmental and occupational health
3121 Internal medicine
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