Adrenocortical carcinoma : presentation and outcome of a contemporary patient series

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Kostiainen , I , Hakaste , L , Kejo , P , Parviainen , H , Laine , T , Löyttyniemi , E , Pennanen , M , Arola , J , Haglund , C , Heiskanen , I & Schalin-Jäntti , C 2019 , ' Adrenocortical carcinoma : presentation and outcome of a contemporary patient series ' , Endocrine , vol. 65 , no. 1 , pp. 166-174 . https://doi.org/10.1007/s12020-019-01918-9

Title: Adrenocortical carcinoma : presentation and outcome of a contemporary patient series
Author: Kostiainen, Iiro; Hakaste, Liisa; Kejo, Pekka; Parviainen, Helka; Laine, Tiina; Löyttyniemi, Eliisa; Pennanen, Mirkka; Arola, Johanna; Haglund, Caj; Heiskanen, Ilkka; Schalin-Jäntti, Camilla
Other contributor: University of Helsinki, Clinicum
University of Helsinki, University of Helsinki
University of Helsinki, Department of Surgery
University of Helsinki, HUS Medical Imaging Center
University of Helsinki, Children's Hospital
University of Helsinki, HUSLAB
University of Helsinki, HUSLAB
University of Helsinki, University of Helsinki
University of Helsinki, II kirurgian klinikka
University of Helsinki, HUS Abdominal Center













Date: 2019-07
Language: eng
Number of pages: 9
Belongs to series: Endocrine
ISSN: 1355-008X
DOI: https://doi.org/10.1007/s12020-019-01918-9
URI: http://hdl.handle.net/10138/305334
Abstract: BackgroundAdrenocortical carcinoma (ACC) is a rare endocrine carcinoma with poor 5-year survival rates of20 Hounsfield Units (HU) for all tumours (median 34 (21-45)), median size 92mm (20-196), Ki67 17% (1-40%), Weiss score 7 (4-9) and Helsinki score 24 (4-48). ACC was more often found in the left than the right adrenal (p5 to>10 years was achieved after repeated surgery of metastases. Overall 5-year survival was 67%, and 96% vs. 26% for ENSAT stage I-II vs. III-IV (p20 on nonenhanced CT but variable tumour size (20-196mm). Malignancy cannot be ruled out by small tumour size only. The 5-year survival of 96% in ENSAT stage I-III compares favourably to previous studies.
Subject: Adrenocortical carcinoma
ENSAT stage
Hounsfield units
Mitotane
Surgery
Complications
Survival
EUROPEAN NETWORK
PROGNOSTIC ROLE
MANAGEMENT
SURVIVAL
CLASSIFICATION
COLLABORATION
ADRENALECTOMY
SOCIETY
DISEASE
ACC
3122 Cancers
3126 Surgery, anesthesiology, intensive care, radiology
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