Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases

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Laulajainen-Hongisto , A , Toppila-Salmi , S K , Luukkainen , A & Kern , R 2020 , ' Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases ' , Frontiers in Cell and Developmental Biology , vol. 8 , 204 . https://doi.org/10.3389/fcell.2020.00204

Title: Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases
Author: Laulajainen-Hongisto, Anu; Toppila-Salmi, Sanna Katriina; Luukkainen, Annika; Kern, Robert
Contributor organization: HUS Head and Neck Center
Korva-, nenä- ja kurkkutautien klinikka
Clinicum
Helsinki University Hospital Area
University of Helsinki
HUS Inflammation Center
Department of Pathology
Department of Dermatology, Allergology and Venereology
Medicum
Date: 2020-03-27
Language: eng
Number of pages: 15
Belongs to series: Frontiers in Cell and Developmental Biology
ISSN: 2296-634X
DOI: https://doi.org/10.3389/fcell.2020.00204
URI: http://hdl.handle.net/10138/315227
Abstract: Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the airways. This review links environmental factors to host epithelial immunity in airway diseases. Understanding altered homeostasis of the airway epithelium might provide important targets for diagnostics and therapy of chronic airway diseases.
Subject: asthma
chronic rhinosinusitis
epithelium
allergic rhinitis (AR)
inflammation
PRIMARY CILIARY DYSKINESIA
MUCOUS CELL METAPLASIA
CHRONIC RHINOSINUSITIS
NASAL POLYPS
BARRIER DYSFUNCTION
CIGARETTE-SMOKE
GENE-EXPRESSION
DIFFERENTIAL EXPRESSION
PERIOSTIN EXPRESSION
RHINOVIRUS INFECTION
1182 Biochemistry, cell and molecular biology
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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