A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

Show full item record



Permalink

http://hdl.handle.net/10138/319734

Citation

Early Growth Genetics Consortium , Bradfield , J P , Vogelezang , S , Pitkänen , N , Leinonen , J T , Lindi , V , Atalay , M , Kähönen , M , Raitakari , O T , Eriksson , J & Widen , E 2019 , ' A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity ' , Human Molecular Genetics , vol. 28 , no. 19 , pp. 3327-3338 . https://doi.org/10.1093/hmg/ddz161

Title: A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
Author: Early Growth Genetics Consortium; Bradfield, Jonathan P.; Vogelezang, Suzanne; Pitkänen, Niina; Leinonen, Jaakko T.; Lindi, Virpi; Atalay, Mustafa; Kähönen, Mika; Raitakari, Olli T.; Eriksson, Johan; Widen, Elisabeth
Contributor: University of Helsinki, Genomics of Sex Differences
University of Helsinki, Johan Eriksson / Principal Investigator
University of Helsinki, Centre of Excellence in Complex Disease Genetics
Date: 2019-10-01
Language: eng
Number of pages: 12
Belongs to series: Human Molecular Genetics
ISSN: 0964-6906
URI: http://hdl.handle.net/10138/319734
Abstract: Although hundreds of genome-wide association studies-implicated loci have been reported for adult obesity-related traits, less is known about the genetics specific for early-onset obesity and with only a few studies conducted in non-European populations to date. Searching for additional genetic variants associated with childhood obesity, we performed a trans-ancestral meta-analysis of 30 studies consisting of up to 13005 cases (>= 95th percentile of body mass index (BMI) achieved 2-18 years old) and 15599 controls (consistently
Subject: SUSCEPTIBILITY LOCI
IDENTIFIES 3
MC3R GENE
MANAGEMENT
VARIANTS
DATABASE
1182 Biochemistry, cell and molecular biology
1184 Genetics, developmental biology, physiology
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
A_Trans_ancestr ... ith_Childhood_Obesity_.pdf 817.2Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record