European Position Paper on Rhinosinusitis and Nasal Polyps 2020

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Fokkens , W J , Lund , V J , Hopkins , C , Hellings , P W , Kern , R , Reitsma , S , Toppila-Salmi , S , Bernal-Sprekelsen , M , Mullol , J , Alobid , I , Anselmo-Lima , W T , Bachert , C , Baroody , F , von Buchwald , C , Cervin , A , Cohen , N , Constantinidis , J , De Gabory , L , Desrosiers , M , Diamant , Z , Douglas , R G , Gevaert , P H , Hafner , A , Harvey , R J , Joos , G F , Kalogjera , L , Knill , A , Kocks , J H , Landis , B N , Limpens , J , Lebeer , S , Lourenco , O , Matricardi , P M , Meco , C , O'Mahony , L , Philpott , C M , Ryan , D , Schlosser , R , Senior , B , Smith , T L , Teeling , T , Tomazic , P V , Wang , D Y , Wang , D , Zhang , L , Agius , A M , Ahlstrom-Emanuelsson , C , Alabri , R , Albu , S , Alhabash , S , Aleksic , A , Aloulah , M , Al-Qudah , M , Alsaleh , S , Baban , M A , Baudoin , T , Balvers , T , Battaglia , P , Bedoya , J D , Beule , A , Bofares , K M , Braverman , I , Brozek-Madry , E , Byaruhanga , R , Callejas , C , Carrie , S , Caulley , L , Chussi , D , de Corso , E , Coste , A , El Hadi , U , Elfarouk , A , Eloy , P H , Farrokhi , S , Felisati , G , Ferrari , M D , Fishchuk , R , Grayson , J W , Goncalves , P M , Grdinic , B , Grgic , V , Hamizan , A W , Heinichen , J V , Husain , S , Ping , T I , Ivaska , J , Jakimovska , F , Jovancevic , L , Kakande , E , Kamel , R , Karpischenko , S , Kariyawasam , H H , Kawauchi , H , Kjeldsen , A , Klimek , L , Krzeski , A , Barsova , G K , Kim , S W , Lal , D , Letort , J J , Lopatin , A , Mahdjoubi , A , Mesbahi , A , Netkovski , J , Tshipukane , D N , Obando-Valverde , A , Okano , M , Onerci , M , Ong , Y K , Orlandi , R , Otori , N , Ouennoughy , K , Ozkan , M , Peric , A , Plzak , J , Prokopakis , E , Prepageran , N , Psaltis , A , Pugin , B , Raftopulos , M , Rombaux , P , Riechelmann , H , Sahtout , S , Sarafoleanu , C-C , Searyoh , K , Rhee , C-S , Shi , J , Shkoukani , M , Shukuryan , A K , Sicak , M , Smyth , D , Snidvongs , K , Kosak , T S , Stjarne , P , Sutikno , B , Steinsvag , S , Tantilipikorn , P , Thanaviratananich , S , Thuy Tran , Urbancic , J , Valiulis , A , de Aparicio , C V , Vicheva , D , Virkkula , P M , Vicente , G , Voegels , R , Wagenmann , M , Wardani , R S , Welge-Lussen , A , Witterick , I , Wright , E , Zabolotniy , D , Zsolt , B & Zwetsloot , C P 2020 , ' European Position Paper on Rhinosinusitis and Nasal Polyps 2020 ' , Rhinology : official organ of the International rhinologic society , vol. 58 , no. Suppl 29 , pp. 1-464 . https://doi.org/10.4193/Rhin20.600

Title: European Position Paper on Rhinosinusitis and Nasal Polyps 2020
Author: Fokkens, Wytske J.; Lund, Valerie J.; Hopkins, Claire; Hellings, Peter W.; Kern, Robert; Reitsma, Sietze; Toppila-Salmi, Sanna; Bernal-Sprekelsen, Manuel; Mullol, Joaquim; Alobid, Isam; Anselmo-Lima, Wilma Terezinha; Bachert, Claus; Baroody, Fuad; von Buchwald, Christian; Cervin, Anders; Cohen, Noam; Constantinidis, Jannis; De Gabory, Ludovic; Desrosiers, Martin; Diamant, Zuzana; Douglas, Richard G.; Gevaert, Philippe H.; Hafner, Anita; Harvey, Richard J.; Joos, Guy F.; Kalogjera, Livije; Knill, Andrew; Kocks, Janwillem H.; Landis, Basile N.; Limpens, Jacqueline; Lebeer, Sarah; Lourenco, Olga; Matricardi, Paolo M.; Meco, Cem; O'Mahony, Liam; Philpott, Carl M.; Ryan, Dermot; Schlosser, Rodney; Senior, Brent; Smith, Timothy L.; Teeling, Thijs; Tomazic, Peter Valentin; Wang, De Yun; Wang, Dehui; Zhang, Luo; Agius, Adrian M.; Ahlstrom-Emanuelsson, Cecilia; Alabri, Rashid; Albu, Silviu; Alhabash, Saied; Aleksic, Aleksandra; Aloulah, Mohammad; Al-Qudah, Mohannad; Alsaleh, Saad; Baban, Muaid Aziz; Baudoin, Tomislav; Balvers, Tijmen; Battaglia, Paolo; Bedoya, Juan David; Beule, Achim; Bofares, Khaled M.; Braverman, Itzhak; Brozek-Madry, Eliza; Byaruhanga, Richard; Callejas, Claudio; Carrie, Sean; Caulley, Lisa; Chussi, Desderius; de Corso, Eugenio; Coste, Andre; El Hadi, Usama; Elfarouk, Ahmed; Eloy, Philippe H.; Farrokhi, Shokrollah; Felisati, Giovanni; Ferrari, Michel D.; Fishchuk, Roman; Grayson, Jessica W.; Goncalves, Paulo M.; Grdinic, Boris; Grgic, Velimir; Hamizan, Aneeza W.; Heinichen, Julio V.; Husain, Salina; Ping, Tang Ing; Ivaska, Justinas; Jakimovska, Frodita; Jovancevic, Ljiljana; Kakande, Emily; Kamel, Reda; Karpischenko, Sergei; Kariyawasam, Harsha H.; Kawauchi, Hideyuki; Kjeldsen, Anette; Klimek, Ludger; Krzeski, Antoni; Barsova, Gabriela Kopacheva; Kim, Sung Wam; Lal, Devyani; Letort, Jose J.; Lopatin, Andrey; Mahdjoubi, Abdelhak; Mesbahi, Alireza; Netkovski, Jane; Tshipukane, Dieudonne Nyenbue; Obando-Valverde, Andres; Okano, Mitsuhiro; Onerci, Metin; Ong, Yew Kwang; Orlandi, Richard; Otori, Nobuyoshi; Ouennoughy, Kheir; Ozkan, Muge; Peric, Aleksandar; Plzak, Jan; Prokopakis, Emmanuel; Prepageran, Nerayanan; Psaltis, Alkis; Pugin, Benoit; Raftopulos, Marco; Rombaux, Philippe; Riechelmann, Herbert; Sahtout, Semia; Sarafoleanu, Caius-Codrut; Searyoh, Kafui; Rhee, Chae-Seo; Shi, Jianbo; Shkoukani, Mahdi; Shukuryan, Arthur K.; Sicak, Marian; Smyth, David; Snidvongs, Kornkiat; Kosak, Tanja Soklic; Stjarne, Par; Sutikno, Budi; Steinsvag, Sverre; Tantilipikorn, Pongsakorn; Thanaviratananich, Sanguansak; Thuy Tran,; Urbancic, Jure; Valiulis, Arunas; de Aparicio, Carolina Vasquez; Vicheva, Dilyana; Virkkula, Paula M.; Vicente, Gil; Voegels, Richard; Wagenmann, Martin; Wardani, Retno S.; Welge-Lussen, Antje; Witterick, Ian; Wright, Erin; Zabolotniy, Dmytro; Zsolt, Bella; Zwetsloot, Casper P.
Other contributor: University of Helsinki, HUS Inflammation Center
University of Helsinki, Korva-, nenä- ja kurkkutautien klinikka




Date: 2020-02-20
Language: eng
Number of pages: 464
Belongs to series: Rhinology : official organ of the International rhinologic society
ISSN: 0300-0729
DOI: https://doi.org/10.4193/Rhin20.600
URI: http://hdl.handle.net/10138/328733
Abstract: The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was published and addresses areas not extensively covered in EPOS2012 such as paediatric CRS and sinus surgery. EPOS2020 also involves new stakeholders, including pharmacists and patients, and addresses new target users who have become more involved in the management and treatment of rhinosinusitis since the publication of the last EPOS document, including pharmacists, nurses, specialised care givers and indeed patients themselves, who employ increasing self-management of their condition using over the counter treatments. The document provides suggestions for future research in this area and offers updated guidance for definitions and outcome measurements in research in different settings. EPOS2020 contains chapters on definitions and classification where we have defined a large number of terms and indicated preferred terms. A new classification of CRS into primary and secondary CRS and further division into localized and diffuse disease, based on anatomic distribution is proposed. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, allergic rhinitis, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. All available evidence for the management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is systematically reviewed and integrated care pathways based on the evidence are proposed. Despite considerable increases in the amount of quality publications in recent years, a large number of practical clinical questions remain. It was agreed that the best way to address these was to conduct a Delphi exercise. The results have been integrated into the respective sections. Last but not least, advice for patients and pharmacists and a new list of research needs are included.
Subject: Paranasal Sinus Diseases
Nasal Polyps
Therapeutics
Diagnosis
Asthma
Prevention and Control
ENDOSCOPIC-SINUS-SURGERY
QUALITY-OF-LIFE
PRIMARY CILIARY DYSKINESIA
CHURG-STRAUSS-SYNDROME
ALLERGIC FUNGAL RHINOSINUSITIS
UPPER RESPIRATORY-TRACT
RANDOMIZED CONTROLLED-TRIAL
PLACEBO-CONTROLLED TRIAL
ACUTE MAXILLARY SINUSITIS
TERM-FOLLOW-UP
3125 Otorhinolaryngology, ophthalmology
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