Age of first alcohol intoxication and psychiatric disorders in young adulthood - A prospective birth cohort study

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Mustonen , A , Alakokkare , A-E , Salom , C , Hurtig , T , Levola , J , Scott , J G , Miettunen , J & Niemelä , S 2021 , ' Age of first alcohol intoxication and psychiatric disorders in young adulthood - A prospective birth cohort study ' , Addictive Behaviors , vol. 118 , 106910 . https://doi.org/10.1016/j.addbeh.2021.106910

Title: Age of first alcohol intoxication and psychiatric disorders in young adulthood - A prospective birth cohort study
Author: Mustonen, Antti; Alakokkare, Anni-Emilia; Salom, Caroline; Hurtig, Tuula; Levola, Jonna; Scott, James G.; Miettunen, Jouko; Niemelä, Solja
Contributor organization: HUS Psychiatry
Clinicum
Department of Psychiatry
Date: 2021-07
Language: eng
Number of pages: 8
Belongs to series: Addictive Behaviors
ISSN: 0306-4603
DOI: https://doi.org/10.1016/j.addbeh.2021.106910
URI: http://hdl.handle.net/10138/330937
Abstract: Objective: Early onset of alcohol use is associated with an increased risk of substance use disorders (SUD), but few studies have examined associations with other psychiatric disorders. Our aim was to study the association between the age of first alcohol intoxication (AFI) and the risk of psychiatric disorders in a Finnish general population sample. Methods: We utilized a prospective, general population-based study, the Northern Finland Birth Cohort 1986. In all, 6,290 15?16-year old adolescents answered questions on AFI and were followed up until the age of 33 years for psychiatric disorders (any psychiatric disorder, psychosis, SUD, mood disorders and anxiety disorders) by using nationwide register linkage data. Cox-regression analysis with Hazard Ratios (HR, with 95% confidence intervals (CI)) was used to assess the risk of psychiatric disorders associated with AFI. Results: Statistically significant associations were observed between AFI and any psychiatric disorder, psychosis, SUDs, and mood disorders. After adjustments for other substance use, family structure, sex and parental psychiatric disorders, AFIs of 13?14 years and
Subject: Alcohol
Adolescent
Birth cohort
Psychiatric disorders
Substance use disorders
DRINKING ONSET
SUBSTANCE USE
CANNABIS USE
RISK
ASSOCIATION
DEPENDENCE
SYMPTOMS
515 Psychology
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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