Type C bovine botulism outbreak due to carcass contaminated non-acidified silage.

Show full item record

Permalink

Citation

Epidemiol Infect. 2008 Jul 7:1-10.

Title: Type C bovine botulism outbreak due to carcass contaminated non-acidified silage.
Author: Myllykoski J; Lindström M; Keto-Timonen R; Söderholm H; Jakala J; Kallio H; Sukura A; Korkeala H
Date: 2008
ISSN: 0950-2688 (Print)
URI: http://dx.doi.org/10.1017/S0950268808000939
http://hdl.handle.net/1975/8295
Abstract: The first reported bovine botulism outbreak in Finland is described. Nine out of 90 cattle on a dairy farm died after being fed non-acidified silage contaminated by animal carcasses. Type C botulinum neurotoxin gene was detected in one heifer by polymerase chain reaction (PCR) and the neurotoxin was detected by the mouse bioassay. Clostridium botulinum type C was isolated from liver samples. The isolated strain was identified with amplified fragment length polymorphism (AFLP) analysis as group III C. botulinum. To our knowledge, this is the first time that a type C bovine botulism outbreak has been diagnosed by PCR and confirmed by subsequent isolation and AFLP identification of the disease strain. The importance of the acidification process in silage production to inhibit C. botulinum toxin production in silage and thus to prevent further botulism outbreaks is emphasized. Nevertheless, preformed toxin in the carcass is not destroyed by acid.


Files in this item

Total number of downloads: Loading...

Files Size Format View
Fig1.pdf 36.31Kb PDF View/Open
Myllykoski et al revised MS.pdf 67.23Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record